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AQA A-Level Biology Paper 2 Insights

Ellena Gilson

5th June 2026

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The AQA A-Level Biology Paper 2 Exam is on Fri 12th June. Here are my observations about which topics haven't been examined for a while and could come up.

It is vital to revise and prepare for ALL topics. This is not a set of predictions for the paper, rather a set of observations of the topics that haven't been deeply assessed for a while.

Good luck everyone!

General observations:

2026

  • Photoionisation (2019)
  • Chemiosmosis / photolysis of water (not yet)
  • Required Practical 8 dehydrogenase activity (2017)
  • ATP synthase (not yet)
  • Respirometer (2022)
  • Required Practical 9 – respiration in single celled organisms
  • Calorimitry / biomass – (gap fill in 2022, last big Q 2020)
  • GPP (2018) , productivity (2019)
  • Fertilisers (2020) leaching and eutrophication (not yet)
  • Gravitropism (not yet)
  • Kinesis
  • Pacinian corpuscle (not yet – specimen paper)
  • Resting potential (2021)
  • No direct question on the action potential / refractory period / axon diameter
  • Antagonistic muscle pairs (not yet)
  • Glomerular filtrate (2020)
  • Loop of Henle (specimen paper)
  • Pedigree (2022)
  • No big epistasis question (2023 small)
  • Variation (2020 / 2023)
  • Directional selection (2018), stabilising selection (none)
  • Genetic drift (not yet)
  • Belt transect (2019)
  • Mutation and cancer (2022)
  • Lack of questions on specific potency of stem cells – last stem cell (2020 / 2018)
  • Epigenetics (2022)
  • RNA interference (2021)
  • Recombinant DNA technology (2020)
  • Reverse transcriptase big question (2017)
  • Plasmids (2020)
  • Genetic counselling and personalised medicine (not yet), screening (2022)
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Ellena Gilson